Djokovic's US Open first-round loss ends run of 78 opening-round Grand Slam wins

Novak Djokovic was defeated by Mariano Navone in the first round of the US Open on August 31, 2026, ending a streak of 78 consecutive opening-round Grand Slam wins.

The four-hour, 36-minute match was his longest first-round major match. It was his first opening-round Grand Slam loss since the 2006 Australian Open. The defeat came as Djokovic made his 20th US Open appearance, joining Connors, Agassi and Lopez.